Original paper
Abstract 2851: Trop-2 inactivates E-cadherin for metastatic diffusion in the absence of EMT
Abstract
Trop-2 is a type I transmembrane glycoprotein, which is overexpressed in the majority of carcinomas, where it drives tumor cell proliferation. In its mature, glycosylated/functionally-competent form, Trop-2 associates with worse prognosis. A global quest was conducted for identifying decisive drivers of cancer metastasis. Cancer cell spheroids, wound healing and cell aggregation assays were utilized to assess cell-cell adhesion capacity....
Paper Details
Title
Abstract 2851: Trop-2 inactivates E-cadherin for metastatic diffusion in the absence of EMT
Published Date
Jul 1, 2021
Journal
Volume
81
Issue
13_Supplement
Pages
2851 - 2851
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Notes
History