Adverse events associated with umbilical catheters: a systematic review and meta-analysis

To determine the incidence of adverse events (AEs) associated with umbilical catheters in the neonatal population. Systematic review and meta-analysis of observational studies and randomized controlled trials published between 2010 and 2020. In total 14,226 umbilical venous catheters (UVCs) and 4228 umbilical arterial catheters (UACs) were included. Overall, 13.4% of UVCs were associated with an AE (95% CI: 10.1–17.0) or 2.4 per 1000 catheter...