Multifunctional antibody-conjugated coiled-coil protein nanoparticles for selective cell targeting
Abstract
Nanostructures decorated with antibodies (Abs) are applied in bioimaging and therapeutics. However, most covalent conjugation strategies affect Abs functionality. In this study, we aimed to create protein-based nanoparticles to which intact Abs can be attached through tight, specific, and noncovalent interactions. Initially considered waste products, bacterial inclusion bodies (IBs) have been used in biotechnology and biomedicine. However, the...
Paper Details
Title
Multifunctional antibody-conjugated coiled-coil protein nanoparticles for selective cell targeting
Published Date
Sep 1, 2021
Journal
Volume
131
Pages
472 - 482
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