Activation of trace amine‐associated receptor 1 attenuates nicotine withdrawal‐related effects

Nicotine addiction is a leading avoidable brain disorder globally. Although nicotine induces a modest reinforcing effect, which is important for the initial drug use, the transition from nicotine use to nicotine addiction involves the mechanisms responsible for the negative consequences of drug abstinence. Recent study suggested that trace amine‐associated receptor 1 (TAAR1) is a promising pharmacological target for the modulation of positive...