Original paper

Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression

Volume: 40, Issue: 1
Published: Jun 26, 2021
Abstract
Background Mesothelial E- and P-selectins substantially mediate the intraperitoneal spread of Pancreatic ductal adenocarcinoma (PDA) cells in xenograft models. In the absence of selectins in the host, the integrin subunit alpha-V (ITGAV, CD51) was upregulated in the remaining metastatic deposits. Here we present the first experimental study to investigate if ITGAV plays a functional role in PDA tumor growth and progression with a particular...
Paper Details
Title
Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression
Published Date
Jun 26, 2021
Volume
40
Issue
1
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