Cathepsin D Activity in Urine of Children and Adolescents Correlates with Cardiovascular Risk

Introduction The RAS and KKS have a role modulating obesity and consequently can contribute to development of associated diseases, such as, diabetes mellitus, dyslipidemia, hypertension and metabolic syndrome. Preliminary studies of our group showed a correlation between diminished levels of the vasodilator peptides, Ang 1–7 and BK, and increased body mass. Also, obese and morbid obese adolescents presented higher levels of Ang I and des‐Arg9BK,...