MO467SINGLE NEPHRON GFR AND GLOMERULAR HYDROSTATIC PRESSURE IN JAPANESE HEALTHY SUBJECTS

Background and Aims Hemodynamic abnormalities such as intraglomerular hypertension and glomerular hyperfiltration associated with the nephron loss are deeply involved in renal damage progression. Recent studies in humans have described a new method to calculate single nephron GFR (SNGFR), which is defined as GFR divided by the estimated total number of non-sclerosed glomeruli. We have previously shown that a higher SNGFR, which indicates...