Takashi Yokoo
Jikei University School of Medicine
Internal medicineUrologyEndocrinologyPathologyRenal functionRegeneration (biology)ImmunologyBiopsyKidney diseaseProteinuriaKidneyKidney transplantationRenal biopsyNephronStem cellTransplantationNephrologyMedicineBiologyGastroenterology
315Publications
28H-index
2,640Citations
Publications 316
Newest
#1Hiroshi SasakiH-Index: 89
#2Satomi IwaiH-Index: 8
Last. Eiji KobayashiH-Index: 53
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#1Rina Oba (Jikei University School of Medicine)H-Index: 1
#2Go Kanzaki (Jikei University School of Medicine)H-Index: 12
Last. Hideo Okonogi (Jikei University School of Medicine)H-Index: 10
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Abstract null null Introduction null Recent studies have demonstrated the pivotal role of complement activation in the pathogenesis of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN). The present study investigated the clinicopathologic and prognostic significance of glomerular C3 deposition in the renal histopathology of patients with ANCA-GN. null null null Methods null We retrospectively identified 142 patients with ANCA-GN from 6 hospitals in Japan (from 2004 to ...
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#1Yukio Maruyama (Jikei University School of Medicine)H-Index: 18
#2Takahito Niikura (Jikei University School of Medicine)H-Index: 4
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
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Anemia treatment is crucial in the management of dialyzed patients. Although Hb and serum ferritin levels are commonly used as indicators for treatment, these values change over time due to changes in policy, drugs for treating anemia, and target levels suggested by clinical guidelines. To clarify long-term changes in anemia-related parameters in Japan, we extracted annual patient data from a newly developed web-based system by the Japanese Society for Dialysis Therapy, the Web-based Analysis of...
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#1Tsuyoshi Takamura (Jikei University School of Medicine)H-Index: 4
#2Hiroshi Sasaki (Jikei University School of Medicine)H-Index: 89
Last. Susumu Tajiri (Jikei University School of Medicine)H-Index: 5
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PURPOSE As a classical xenotransplantation model, porcine kidneys have been transplanted into the lower abdomen of non-human primates. However, we have improved upon this model by using size-matched grafting in the orthotopic position. The beneficial aspects and surgical details of our method are reported herein. METHODS Donors were two newborn pigs (weighting 5 to 6 kg) and recipients were two cynomolgus monkeys (weighting, approximately, 7 kg). After bilateral nephrectomy, kidneys were cold-tr...
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#1Kosuke Honda (Jikei University School of Medicine)H-Index: 1
#2Satoru Kuriyama (Jikei University School of Medicine)H-Index: 18
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
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BACKGROUND Insulin-like growth factor-1 (IGF-1) acts on glucose and protein metabolism and human growth and also influences blood pressure and renal function. This study investigated whether the single-nucleotide polymorphism of IGF-1, rs35767, plays a role in metabolic syndrome indicators, including blood pressure, glucose metabolism, uric acid levels, and renal function. METHODS In this retrospective longitudinal cohort study, blood samples from 1506 Japanese individuals were collected and use...
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#1Kana Asari (Jikei University School of Medicine)H-Index: 1
#2Yukio Maruyama (Jikei University School of Medicine)H-Index: 18
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
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The aim of this study was to compare the changes in peritoneal function and residual renal function in the first year between diabetic and non-diabetic patients receiving peritoneal dialysis (PD). We extracted 73 incident PD patients (male, 73%; age, 59 ± 15 years) from a previous cohort, and investigated the changes in PD-related parameters, including the dialysate to plasma ratio of creatinine (D/P Cr) and Kt/V. D/P Cr increased in non-diabetics, whereas it did not change significantly in diab...
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#2Go Kanzaki (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
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Sudden unexpected death in epilepsy (SUDEP) has been defined as a sudden/unexpected, witnessed/unwitnessed, nontraumatic, and nondrowning death in epileptic patients with/without seizure evidence and documented status epilepticus. Identified as the leading cause of epilepsy-related deaths, SUDEP cases are highly unrecognized and underreported due to diagnostic difficulty. We report a case of a successfully revived hemodialysis patient who developed cardiopulmonary arrest after a witnessed convul...
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#1Satoshi Matsuoka (UTokyo: University of Tokyo)H-Index: 61
#2Hidehiro Kaneko (UTokyo: University of Tokyo)H-Index: 14
Last. Issei Komuro (UTokyo: University of Tokyo)H-Index: 115
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Background We aimed to explore the association between the blood pressure (BP) classification defined by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline and the prevalence of retinal atherosclerosis. Methods This study was a retrospective observational cross-sectional analysis using the JMDC Claims Database. We analyzed 280,599 subjects not taking any antihypertensive medications. According to the 2017 ACC/AHA guideline, each subject was categorized as ha...
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#1Sahoko Kamejima (Jikei University School of Medicine)H-Index: 3
#2Izumi Yamamoto (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
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The eligibility for kidney donation and long-term post-donation renal prognosis of patients with Gitelman syndrome (GS) are unknown. We herein report a 44-year-old woman with GS who donated her kidney for transplant. A gene sequence analysis revealed compound heterozygous mutations of T180K and L858H in the SLC12A3 gene. Since transplantation, the renal function and serum potassium and magnesium levels of the donor and recipient have remained stable for seven years with careful monitoring and su...
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