[18F]fluoro-para-hydroxyphenethylguanidine ([18F]pHPG): A Novel PET Radiotracer for Imaging of Metastatic Paraganglioma in Humans

1370 null Objectives: null null We present our initial experience of a novel PET radiotracer, [18F]fluoro-para-hydroxyphenethylguanidine ([18F]pHPG), a substrate of the norepinephrine transporter (NET) and the vesicular monoamine transporter type 2 (VMAT2), for imaging of patients with metastatic paraganglioma (n=2 to date). [18F]pHPG has been previously reported to localize in presynaptic sympathetic nerve terminals in organs that have high...