Review paper
3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion
Volume: 9, Issue: 7, Pages: 3729 - 3741
Published: Jun 3, 2021
Abstract
Background: Tumorigenesis is attributed to the interactions of cancer cells with the tumor microenvironment through both biochemical cues and physical stimuli. Increased matrix deposition and realignment of the collagen fibers are detected by cancer cells, inducing epithelial-to-mesenchymal transition, which in turn stimulates cell motility and invasiveness. Methods: This review provides an overview of current research on the role of the...
Paper Details
Title
3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion
Published Date
Jun 3, 2021
Volume
9
Issue
7
Pages
3729 - 3741
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