Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies

Late-life cognitive function is heterogeneous, ranging from no decline to severe dementia. Prior studies of cognitive trajectories have tended to focus on a single measure of global cognition or individual tests scores, rather than considering longitudinal performance on multiple tests simultaneously.The current study aimed to examine cognitive trajectories from two independent datasets to assess whether similar patterns might describe...