Identification of Potential Pathogenic Super-Enhancers-Driven Genes in Pulmonary Fibrosis
Abstract
Abnormal fibroblast differentiation into myofibroblast is a crucial pathological mechanism of pulmonary fibrosis (PF). Super-enhancers, a newly discovered cluster of regulatory elements, are regarded as the regulators of cell identity. We speculate that abnormal activation of super-enhancers must be involved in the pathological process of PF. This study aims to identify potential pathogenic super-enhancer-driven genes in PF. Differentially...
Paper Details
Title
Identification of Potential Pathogenic Super-Enhancers-Driven Genes in Pulmonary Fibrosis
Published Date
May 12, 2021
Journal
Volume
12
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