Frontiers in Genetics
IF
4.60
Papers
4,835
Papers 8,228
1 page of 823 pages (8,228 results)
Newest
Characterization of genetic variations that are associated with gene expression levels is essential to understand cellular mechanisms that underline human complex traits. Expression quantitative trait loci (eQTL) mapping attempts to identify genetic variants, such as single nucleotide polymorphisms (SNPs), that affect the expression of one or more genes. With the availability of a large volume of gene expression data, it is necessary and important to develop fast and efficient statistical and co...
Source
Wild species related to cultivated tomato are essential genetic resources in breeding programs focused on food security to face future challenges. Ecogeographic analysis allow to identify species adaptive ranges and most relevant environmental variables explaining their patterns of actual distribution. This information is relevant for the rescue, conservation, genetic characterization, documentation and use of wild tomatoes and close related species. The objective of this research was to identif...
Source
#2Chong LiuH-Index: 2
Last. Ke DongH-Index: 2
view all 7 authors...
To investigate the expression levels and prognostic value of CD73 in lung cancer. And moreover, to identify the effect and potential mechanism of CD73 on lung cancer cells proliferation and migration. CD73 expression levels in lung cancer were analyzed base on GEPIA2 and GEO database. GEPIA2 and Kaplan-Meier Plotter (KM Plotter) was used to analyzed the correlation between CD73 expression and prognosis. GEO dataset were analyzed via GEO2R. CD73 overexpression cell model was construction via reco...
Source
#1Shahid Niaz KhanH-Index: 17
#2Rehman AliH-Index: 2
Last. Sultan AyazH-Index: 7
view all 8 authors...
Background: Understanding the genetic diversity of Plasmodium species through polymorphic studies can assist in the designing of more effective control strategies of malaria like new drug formulation and development of a vaccine. Pakistan is moderate endemic for Plasmodium falciparum, but little is known about the genetic diversity of this parasite. This study aimed to investigate the molecular diversity of P. falciparum based on msp-1 and msp-2 in the malaria-endemic regions of the Khyber Pakht...
Source
TCP proteins are plant-specific transcription factors that have multipurpose roles in plant developmental procedures and stress responses. Therefore, a genome-wide analysis was performed to categorize the TCP genes in the rapeseed genome. In this study, a total of 80 BnTCP genes were identified in the rapeseed genome and grouped into two main classes (PCF and CYC/TB1) according to phylogenetic analysis. The universal evolutionary analysis uncovered that BnTCP genes had experienced segmental dupl...
Source
#1Xinmei WenH-Index: 1
#2Wenjia ZhuH-Index: 1
Last. Min XuH-Index: 2
view all 14 authors...
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease, characterized by great variety of both clinical presentations and genetic causes. Previous studies had identified two different missense mutations in SOD1 (p.R116C and p.R116G) causing familial ALS. In this study, we report a novel heterozygous missense mutation in the SOD1 gene (p.R116S) in a family with inherited ALS manifested as fast deteriorating pure lower motor neuron symptoms. The patient displayed simil...
Source
#1Qinrui YangH-Index: 3
#2Jinglei QianH-Index: 1
Last. Jianhui XieH-Index: 16
view all 9 authors...
Source
There is increasing evidence that species diversity is underestimated in the current taxonomy of widespread freshwater fishes. The bagrid species T.albomarginatus s.l. is mainly distributed in the lowlands of South China as currently identified. A total of forty localities (including the type locality), which covers most of its known range, were sampled. Molecular phylogenetic analyses based on concatenated mtDNA and nuclear genes recover nine highly-supported lineages clustering into eight geog...
Source
Source
Autosomal recessive non-syndromic deafness-28 (DFNB28) is characterized by prelingual, profound sensorineural hearing loss (HL). The disease is related to variants of the TRIOBP gene. TRIO and F-actin binding protein (TRIOBP) plays crucial roles in modulating the assembly of the actin cytoskeleton and are responsible for the proper structure and function of stereocilia in the inner ear. This study aimed to identify pathogenic variants in a patient with HL. Genomic DNA obtained from a 33-year-old...
Source
12345678910
Top fields of study
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.