Spatially Localized Immunotherapy: A Perfect Combination With Radiation Therapy?

Immunotherapy has transformed the landscape of cancer therapy, enabling prolonged disease control in patients with metastatic cancers that were previously incurable. However, intrinsic and acquired resistance to immunotherapy remain major clinical challenges, and there is a pressing need for strategies to overcome immunotherapy resistance mechanisms. In this context, radiation therapy (RT) continues to be investigated, with accumulating evidence...