Review paper
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine
Abstract
Adaptive thermogenesis has attracted much attention because of its ability to increase systemic energy expenditure and to counter obesity and diabetes1-3. Recent data have indicated that thermogenic fat cells use creatine to stimulate futile substrate cycling, dissipating chemical energy as heat4,5. This model was based on the super-stoichiometric relationship between the amount of creatine added to mitochondria and the quantity of oxygen...
Paper Details
Title
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine
Published Date
May 12, 2021
Journal
Volume
593
Issue
7860
Pages
580 - 585
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