The functional role of decorin in corneal neovascularization in vivo
Abstract
Our earlier decorin (Dcn) gene overexpression studies found that the targeted Dcn gene transfer into the cornea inhibited corneal angiogenesis in vivo using a rabbit model. In this study, we tested the hypothesis that anti-angiogenic effects of decorin in the cornea are mediated by alterations in a normal physiologic balance of pro- and anti-angiogenic factors using decorin deficient (Dcn-/-) and wild type (Dcn+/+) mice. Corneal...
Paper Details
Title
The functional role of decorin in corneal neovascularization in vivo
Published Date
Jun 1, 2021
Journal
Volume
207
Pages
108610 - 108610
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