Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Randomised, controlled trials and meta-analyses have shown the survival benefit of concomitant chemoradiotherapy or hyperfractionated radiotherapy in the treatment of locally advanced head and neck cancer. However, the relative efficacy of these treatments is unknown. We aimed to determine whether one treatment was superior to the other.We did a frequentist network meta-analysis based on individual patient data of meta-analyses evaluating the...