Prevalence of Anxiety and Depression in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis

Background: Inflammatory bowel disease (IBD) is a lifelong condition without a cure. Due to bidirectional communication, via the gut-brain axis, as well as the chronicity of symptoms, impaired quality of life, and reduced social functioning, patients with IBD may experience common mental disorders, including anxiety and depression. However, uncertainties remain about the magnitude of this problem. We conducted a systematic review and...