Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia
Abstract
Acute myeloid leukemia (AML) is the most common acute leukemia, characterized by a heterogeneous genetic landscape contributing, among others, to the occurrence of metabolic reprogramming. Autophagy, a key player on metabolism, plays an essential role in AML. Here, we examined the association of three potentially functional genetic polymorphisms in the ATG10 gene, central for the autophagosome formation. We screened a multicenter cohort...
Paper Details
Title
Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia
Published Date
Mar 16, 2021
Journal
Volume
13
Issue
6
Pages
1344 - 1344
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