Original paper
Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
Abstract
To prevent damage to the host or its commensal microbiota, epithelial tissues must match the intensity of the immune response to the severity of a biological threat. Toll-like receptors allow epithelial cells to identify microbe associated molecular patterns. However, the mechanisms that mitigate biological noise in single cells to ensure quantitatively appropriate responses remain unclear. Here we address this question using single cell and...
Paper Details
Title
Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
Published Date
Mar 23, 2021
Journal
Volume
12
Issue
1
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Notes
History