Magnetic-core-based silibinin nanopolymeric carriers for the treatment of renal cell cancer

Silibinin offers potential anticancer effect with less aqueous solubility and high permeability. The present study aimed to develop biocompatible magnetic-core-based nanopolymeric carriers of poly (D, l-lactide-co-glycolic) acid (PLGA) encapsulated silibinin for the sustained release action on renal cancerous cell. The synthesized iron oxide nanoparticles were prepared by precipitation method via encapsulation of silibinin in PLGA network using...