Prognostic significance of concurrent gene mutations in intensively treated patients with IDH-mutated AML, an ALFA study
Abstract
In patients with isocitrate dehydrogenase (IDH)-mutated acute myeloid leukemia (AML) treated by intensive chemotherapy (IC), prognostic significance of co-occurring genetic alterations and allogeneic hematopoietic stem cell transplantation (HSCT) are of particular interest with the advent of IDH1/2 mutant inhibitors. We retrospectively analyzed 319 patients with newly diagnosed AML (127 with IDH1, 135 with IDH2R140, and 57 with IDH2R172...
Paper Details
Title
Prognostic significance of concurrent gene mutations in intensively treated patients with IDH-mutated AML, an ALFA study
Published Date
Feb 24, 2021
Journal
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