Original paper
Meteorin-like/Meteorin-β protects heart against cardiac dysfunction
Abstract
Meteorin-like/Meteorin-β (Metrnl/Metrnβ) is a secreted protein produced by skeletal muscle and adipose tissue that exerts metabolic actions that improve glucose metabolism. The role of Metrnβ in cardiac disease is completely unknown. Here, we show that Metrnβ-null mice exhibit asymmetrical cardiac hypertrophy, fibrosis, and enhanced signs of cardiac dysfunction in response to isoproterenol-induced cardiac hypertrophy and aging. Conversely,...
Paper Details
Title
Meteorin-like/Meteorin-β protects heart against cardiac dysfunction
Published Date
Feb 26, 2021
Volume
218
Issue
5
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Notes
History