This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.
Original paper

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

Science44.70
Volume: 371, Issue: 6531
Published: Feb 19, 2021
Abstract
Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is generally associated with drug target modification, enzymatic inactivation, and/or transport rather than metabolic processes. Evolution experiments of Escherichia coli rely on growth-dependent selection, which may provide a limited view of the antibiotic resistance landscape. We sequenced and analyzed E. coli adapted to representative antibiotics at...
Paper Details
Title
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
Published Date
Feb 19, 2021
Journal
Volume
371
Issue
6531
© 2025 Pluto Labs All rights reserved.
Step 1. Scroll down for details & analytics related to the paper.
Discover a range of citation analytics, paper references, a list of cited papers, and more.