Antibody-induced procoagulant platelets in severe COVID-19 infection

Blood20.30
Volume: 137, Issue: 8, Pages: 1061 - 1071
Published: Feb 25, 2021
Abstract
The pathophysiology of COVID-19–associated thrombosis seems to be multifactorial. We hypothesized that COVID-19 is accompanied by procoagulant platelets with subsequent alteration of the coagulation system. We investigated depolarization of mitochondrial inner transmembrane potential (ΔΨm), cytosolic calcium (Ca2+) concentration, and phosphatidylserine (PS) externalization. Platelets from COVID-19 patients in the intensive care unit (ICU; n =...
Paper Details
Title
Antibody-induced procoagulant platelets in severe COVID-19 infection
Published Date
Feb 25, 2021
Journal
Volume
137
Issue
8
Pages
1061 - 1071
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