MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment
Volume: 542, Pages: 65 - 72
Published: Feb 1, 2021
Abstract
Dental fluorosis is characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. Excess fluoride could have effects on the ERK signaling, which is essential for the ameloblasts differentiation and tooth development. MAP kinase phosphatase-1 (MKP-1) plays a critical role in regulating ERK related kinases. However, the role of MKP-1 in ameloblast and the mechanisms of MKP-1/ERK signaling in...
Paper Details
Title
MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment
Published Date
Feb 1, 2021
Volume
542
Pages
65 - 72
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