The complexity of DLB: U.S.‐based Dementia with Lewy Body Consortium

Background The clinical syndrome of dementia with Lewy bodies (DLB) is well defined with good positive predictive value for the presence of Lewy body pathology at autopsy. However, the presence of Lewy body pathology in dementia is not always linked to the clinical syndrome of DLB, particularly early in the clinical course (e.g., prodromal and mild cognitive impairment), and co‐pathologies are quite frequent. This clinical and pathologic...