VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk

Volume: 40, Issue: 5, Pages: 964 - 979
Published: Dec 9, 2020
Abstract
It is well established that a subset of cells within primary breast cancers can undergo an epithelial-to-mesenchymal transition (EMT), although the role of EMT in metastasis remains controversial. We previously demonstrated that breast cancer cells that had undergone an oncogenic EMT could increase metastasis of neighboring cancer cells via non-canonical paracrine-mediated activation of GLI activity that is dependent on SIX1 expression in the...
Paper Details
Title
VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk
Published Date
Dec 9, 2020
Journal
Volume
40
Issue
5
Pages
964 - 979
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