Autoreactive T cells in pemphigus: perpetrator and target.
Volume: 156, Issue: 2, Pages: 124 - 133
Published: Apr 1, 2021
Abstract
Pemphigus vulgaris (PV) is an autoimmune blistering disease, in which autoantibodies against epidermal cadherins, such as desmoglein (Dsg)1 and Dsg3, lead to the development of blisters and erosions on the skin and mucous membranes. Autoreactive CD4+ T cells are essential for the induction and perpetuation of the disease by interaction with B cells producing autoantibodies. PV has a strong genetic association with certain human leucocyte antigen...
Paper Details
Title
Autoreactive T cells in pemphigus: perpetrator and target.
Published Date
Apr 1, 2021
Volume
156
Issue
2
Pages
124 - 133
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