Green synthesis of nanoparticles has attracted significant attention as an alternative to chemical synthesis procedure. The bulk availability of plants, microbial biomass and the use of eco-friendly solvents has significantly reduced the cost in addition to the hazards associated with the chemical synthesis of the nanoparticle. In this study, we demonstrated the biosynthesis of titanium nanoparticles (TiO2NPs) with the extract of Trichoderma citrinoviridae as a reducing agent. The physicochemical properties of biogenic TiO2NPs were studied using FESEM, Zeta sizer, FTIR and XRD. The size (10–400 nm), morphology, crystallinity, zeta potential (29.5 mV), and polydispersity index (0.327) suggested that the biogenic TiO2NPs were polymorphic, crystalline and stable. FESEM revealed that the synthesized TiO2NPs were majorly irregular, and some interesting TiO2NPs structures, i.e., triangular, pentagonal, spherical and rod were also observed. The biogenic TiO2NPs showed excellent antibacterial activity (100 µg/mL) against planktonic cells of extremely drug-resistant (XDR) Pseudomonas aeruginosa clinical isolates. The TiO2NPs also had better antioxidant potential as compared to standard gallic acid. This study indicates the use of T. citrinoviridae for synthesizing biogenic TiO2NPs and their potential use against XDR bacteria.
Introduction The efficacy of several antimicrobial agents has been hindered due to the increasing frequency of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. So, the need for new antibacterial drugs or drug combinations is urgent. Recently, desirable antibacterial effects were reported for many metals nanoparticles such as TiO2 nanoparticles (TDNs). Purpose This study aims to investigate the prevalence of MDR P. aeruginosa and assess the efficiency of TDN in the treatment of MDR P. a...
#2James S. Lewis(OHSU: Oregon Health & Science University)H-Index: 11
Last. James S. Lewis(OHSU: Oregon Health & Science University)H-Index: 35
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The CLSI Subcommittee on Antimicrobial Susceptibility Testing is a volunteer-led, multidisciplinary consensus body that develops and publishes standards and guidelines (among other products) for antimicrobial susceptibility testing (AST) methods and results interpretation in the United States and internationally. The Subcommittee (SC) meets face-to-face twice yearly, and its working groups are active throughout the year via teleconferences. All meetings are open to the public. Participants inclu...
Last. Asma Ayaz(QAU: Quaid-i-Azam University)H-Index: 11
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Nanoparticles as biomedicine has made a crucial role in health biotechnology. Different transition metals in various forms playing role in nanotechnological advances and biological applications. Silver as one of the nontoxic, safe inorganic antibacterial agents and can serve as replacement of antibiotics. Present research is based on biogenic synthesis of silver nanoparticles (Ag-NPs) as potential antibiotics from fungal metabolites of Penicillium oxalicum. We used different analytical technique...
#1Nan Yao Lee(NCKU: National Cheng Kung University)H-Index: 30
#2Wen Chien Ko(NCKU: National Cheng Kung University)H-Index: 69
Last. Po-Ren Hsueh(NTU: National Taiwan University)H-Index: 105
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Nanotechnology, the use of materials with dimensions on the atomic or molecular scale, has become increasingly utilized for medical applications and is of great interest as an approach to kill or reduce the activity of numerous microorganisms. Infections caused by multidrug-resistant organisms (MDROs) are emerging causes of morbidity and mortality worldwide. The optimal treatment route for infections caused by MDROs is often unclear, and the antibiotic options are limited. These challenges highl...
Last. Sangram K. Lenka(The Energy and Resources Institute)H-Index: 12
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Abstract Antimicrobial resistance (AMR) is a serious concern in pathogenic bacteria. As a new approach to addressing AMR, we report here the green synthesis of vanillin capped gold nanoparticles (VAuNPs) using the popular flavouring molecule vanillin (C8H8O3) as a reducing and capping agent. Physicochemical characterization revealed that the synthesised VAuNPs were stable and crystalline in nature. VAuNPs were non-bactericidal even at high concentration (>2000 μg/ml). The antibiotic potentiation...
Abstract Present investigation is focused on the development of environment friendly protocol for ZnO nanoparticles synthesis using mycelial free filtrate of unexplored endophytic fungus Cochliobolus geniculatus. Zinc metal tolerant endophyte was isolated from leaves of Nothapodytes foetida and identified based on rDNA internal transcribed spacer region sequence. Surface plasmon resonance examined by UV–VIS spectroscopy analysis confirmed the synthesis of ZnO nanoparticles; exhibiting a band gap...
#2P. Pourali(IAU: Islamic Azad University)H-Index: 1
Last. S. Dolatabadi(IAU: Islamic Azad University)H-Index: 1
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Abstract Objective The emerging microbial drug resistance has limited the choices of treatments for infectious diseases. Application of drugs conjugated with nanoparticles is among the strategies to subside the chance of acquiring resistance and increase the potency of current antibiotics. This study was conducted to produce gold nanoparticles (GNPs) by Fusarium oxysporum to evaluate the antibacterial activity of GNPs conjugated with tetracycline under different conditions. Material and Methods ...
#1Jagpreet Singh(Sri Guru Granth Sahib World University)H-Index: 15
#2Tanushree Dutta(SNBNCBS: S.N. Bose National Centre for Basic Sciences)H-Index: 11
Last. Pawan Kumar(JU: University of Jammu)H-Index: 28
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In materials science, “green” synthesis has gained extensive attention as a reliable, sustainable, and eco-friendly protocol for synthesizing a wide range of materials/nanomaterials including metal/metal oxides nanomaterials, hybrid materials, and bioinspired materials. As such, green synthesis is regarded as an important tool to reduce the destructive effects associated with the traditional methods of synthesis for nanoparticles commonly utilized in laboratory and industry. In this review, we s...
Abstract In recent years, biosynthesis of nanoparticles has received considerable attention due to the growing need to develop clean and nontoxic chemicals, low-cost approaches, eco - friendly solvents and renewable materials. In the current study, the biosynthesis of TiO 2 nanoparticles (TiO 2 NPs) was attained by a chemical and biosynthesized method by using the aqueous leaf extract of Trigonella foenum-graecum (TF-TiO 2 NP). TiO 2 NPs were characterized by FTIR, UV, XRD, HR-TEM and HR-SEM met...
#2Olga Rubilar(UFRO: University of La Frontera)H-Index: 24
Last. Amedea B. Seabra(UFABC: Universidade Federal do ABC)H-Index: 38
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Much progress has been achieved in the preparation and application of engineered nanoparticles (NPs) in the field of medicine, mainly for antibacterial and antiviral applications. In the war against bacteria and viruses, besides traditional antibiotics and antiviral drugs, metal-based nanoparticles, such as silver (AgNPs), copper (CuNPs), copper oxides (CuO-NPs), iron oxide (FeO-NPs), zinc oxide (ZnO-NPs), and titanium oxide (TiO2-NPs) have been used as potent antimicrobial agents. These nanopar...
Nanoparticles (NPs) are rapidly adopted in agriculture to improve plant growth and development. Nano-priming is one such strategy that utilizes NPs to enhance seed germination, seedling vigor, and improve crop resilience. This study is the first attempt to compare the effects of silver and titanium oxide NPs (TcAgNPs and TcTiO2NPs) myco-synthesized using Trichoderma citrinoviride extract as seed priming agents. Different concentrations of TcAgNPs and TcTiO2NPs (25, 50, 100, 200, and 400 µg/mL) w...
Water, one of the crucial and the pillar resources to every living thing, could be polluted day to day by different causes such as expansion in industrialization, rapid increment in population size, the threat of climate, and growth of urbanization. The existence of a number of organic dyes, detergents, and pesticides from industrial effluents could lead to severe diseases and even to the death of human beings. Currently, remediation of those hazardous organic contaminants using semiconductor me...