Inhibition of 4NQO-induced oral squamous cell carcinoma progression by novel TGF-β inhibitors and PD-L1 antibodies
Abstract
Background: TGF-β is a key regulator of oral squamous cell carcinoma (OSCC) progression and its potential role as a therapeutic target has been investigated with a limited success. This study evaluates two novel TGF-β inhibitors as mono or combinatorial therapy with PD-L1 antibodies (Abs) in a murine OSCC model. The inhibitors were developed in Dr. Andrew Hinck‘s laboratory and have been previously...
Paper Details
Title
Inhibition of 4NQO-induced oral squamous cell carcinoma progression by novel TGF-β inhibitors and PD-L1 antibodies
Published Date
Oct 1, 2020
Journal
Volume
138
Pages
S19 - S20
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Notes
History