Improved Characterization of Diffusion in Normal and Cancerous Prostate Tissue Through Optimization of Multicompartmental Signal Models

Multicompartmental modeling outperforms conventional diffusion-weighted imaging (DWI) in the assessment of prostate cancer. Optimized multicompartmental models could further improve the detection and characterization of prostate cancer.To optimize multicompartmental signal models and apply them to study diffusion in normal and cancerous prostate tissue in vivo.Retrospective.Forty-six patients who underwent MRI examination for suspected prostate...