Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease
Abstract
Multiple system atrophy (MSA) is a rare neurodegenerative disease characterized by intracellular accumulations of α-synuclein and nerve cell loss in striatonigral and olivopontocerebellar structures. Epidemiological and clinical studies have reported potential involvement of autoimmune mechanisms in MSA pathogenesis. However, genetic etiology of this interaction remains unknown. We aimed to investigate genetic overlap between MSA and 7...
Paper Details
Title
Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease
Published Date
Oct 27, 2020
Journal
Volume
36
Issue
2
Pages
449 - 459
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History