Suboptimal Dosimetric Coverage Of Pretherapeutic FDG PET/CT Hotspots Is Associated With Distant Recurrence After Chemoradiotherapy For Locally Advanced Cervical Cancer

Areas of high uptake on Pre-treatment 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), denoted as “hotspots”, have been identified as preferential sites of local relapse. The purpose of this study was to analyze the dosimetric coverage of these hotspots with high dose-rate brachytherapy (BT) Forty-two patients with recurrence after CRT for CC were matched to 42 patients without recurrence. Mean...