Review paper
Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia
Abstract
Many epithelia secrete bicarbonate-rich fluid to generate flow, alter viscosity, control pH and potentially protect luminal and intracellular structures from chemical stress. Bicarbonate is a key component of human bile and impaired biliary bicarbonate secretion is associated with liver damage. Major efforts have been undertaken to gain insight into acid-base homeostasis in cholangiocytes and more can be learned from analogous secretory...
Paper Details
Title
Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia
Published Date
Feb 1, 2021
Journal
Volume
74
Issue
2
Pages
428 - 441
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