Modelling Neurocognitive Change Using Brain Substructure Dosimetry In Adults With Primary Brain Tumors

The contribution of radiotherapy (RT) dose to brain substructures on neurocognitive function in adults is unclear, beyond the known role of the hippocampus. The goal of this study was to identify brain substructures associated with neurocognitive decline in adults treated with RT for primary brain tumors. In this retrospective cohort study, adults with a primary brain tumor treated with fractionated photon RT at a single institution were...