Original paper
Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
Abstract
Continuing recalcitrance to therapy cements pancreatic cancer (PC) as the most lethal malignancy, which is set to become the second leading cause of cancer death in our society. The study aim was to investigate the association between DNA damage response (DDR), replication stress, and novel therapeutic response in PC to develop a biomarker-driven therapeutic strategy targeting DDR and replication stress in PC.We interrogated the transcriptome,...
Paper Details
Title
Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
Published Date
Jan 1, 2021
Journal
Volume
160
Issue
1
Pages
362 - 377.e13
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Notes
History