Review paper

Gold nanoparticle‑mediated delivery of paclitaxel and nucleic acids for cancer therapy (Review)

Volume: 22, Issue: 6, Pages: 4475 - 4484
Published: Oct 11, 2020
Abstract
Paclitaxel is a potent antineoplastic agent, but poor solubility and resistance have limited its use. Gold nanoparticles (AuNPs) are widely studied as drug carriers because they can be engineered to prevent drug insolubility, carry nucleic acid payloads for gene therapy, target specific tumor cell lines, modulate drug release and amplify photothermal therapy. Consequently, the conjugation of paclitaxel with AuNPs to improve antiproliferative and...
Paper Details
Title
Gold nanoparticle‑mediated delivery of paclitaxel and nucleic acids for cancer therapy (Review)
Published Date
Oct 11, 2020
Volume
22
Issue
6
Pages
4475 - 4484
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