Original paper
Does the administration of preoperative pembrolizumab lead to sustained remission post-cystectomy? First survival outcomes from the PURE-01 study☆
Abstract
•The PURE-01 study tested neoadjuvant pembrolizumab in patients with muscle invasive bladder cancer.•Pembrolizumab has shown promising activity in this setting, reaching 38.5% of complete response (ypT0ypN0).•Event-free survival is also encouraging with 84.5% and 71.7% rates at 12 and 24 months from immunotherapy initiation.•Survival benefit seems spread to all pathological response subgroups with the exception of ypN+ patients.•Molecular...
Paper Details
Title
Does the administration of preoperative pembrolizumab lead to sustained remission post-cystectomy? First survival outcomes from the PURE-01 study☆
Published Date
Dec 1, 2020
Journal
Volume
31
Issue
12
Pages
1755 - 1763
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History