Andrea Necchi
Vita-Salute San Raffaele University
Internal medicineRadiologyUrologyOncologyCystectomyChemotherapyGerm cell tumorsImmunotherapyCisplatinPembrolizumabBladder cancerMetastatic Urothelial CarcinomaMuscle invasiveIn patientOpen labelUrothelial carcinomaUrothelial cancerPhases of clinical researchCancer researchMedicine
Publications 198
#1Giovanni Cacciamani (SC: University of Southern California)H-Index: 17
Last. Maria J. Ribal (University of Barcelona)H-Index: 35
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Abstract null null The association between tobacco use and urothelial cancer of the bladder is well known. Given the worsening tobacco epidemic, here we make the case for systematic targeted points of intervention for urologists and other professionals to intervene against bladder cancer. Awareness of contemporary checkpoints where we can intervene for counseling patients may help medical education in a tobacco-pandemic difficult setting.
#1Armando Stabile (UniSR: Vita-Salute San Raffaele University)H-Index: 17
#2A. Pellegrino (UniSR: Vita-Salute San Raffaele University)H-Index: 1
Last. Daniele Raggi (UniSR: Vita-Salute San Raffaele University)H-Index: 19
view all 14 authors...
Abstract null null Context null The role of positron emission tomography/computed tomography (PET/CT) with prostate-specific membrane antigen (PSMA) in the primary staging for patients with prostate cancer (PCa) is still debated. null null null Objective null To analyze published studies reporting the accuracy of PSMA PET/CT for detecting lymph node invasion (LNI) at pelvic lymph node dissection (PLND). null null null Evidence acquisition null A search of PubMed/MEDLINE, Cochrane library’s Centr...
#1A. Gordon RobertsonH-Index: 32
#2Khyati Meghani (NU: Northwestern University)
Last. Vadim I. NazarovH-Index: 5
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Checkpoint immunotherapy (CPI) has increased survival for some patients with advanced stage bladder cancer (BCa). However, most patients do not respond. Here, we characterized the tumor and immune microenvironment in pre- and post-treatment tumors from the PURE01 neoadjuvant pembrolizumab immunotherapy trial, using a consolidative approach that combined transcriptional and genetic profiling with digital spatial profiling. We identified five distinctive genetic and transcriptomic programs associa...
#1Marco BandiniH-Index: 24
#2Filippo PederzoliH-Index: 13
Last. Andrea SaloniaH-Index: 82
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#1Jonathan E. Rosenberg (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 60
#2Matthew D. GalskyH-Index: 63
Last. B. NelsonH-Index: 9
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#1Andrea NecchiH-Index: 13
#2Petros GrivasH-Index: 22
Last. Douglas A. Mata (Foundation Medicine)H-Index: 2
view all 15 authors...
#10Jeffrey S. Ross (State University of New York Upstate Medical University)H-Index: 60
#1Andrea NecchiH-Index: 13
#2Petros GrivasH-Index: 22
Last. Jeffrey S. Ross (State University of New York Upstate Medical University)H-Index: 60
view all 10 authors...
#1Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 138
#2Marco Moschini (UniSR: Vita-Salute San Raffaele University)H-Index: 27
Last. Alberto Briganti (UniSR: Vita-Salute San Raffaele University)H-Index: 96
view all 6 authors...
#1Laura Martinez-Vidal (UniSR: Vita-Salute San Raffaele University)
#2Valentina Murdica (UniSR: Vita-Salute San Raffaele University)H-Index: 7
Last. Massimo Alfano (UniSR: Vita-Salute San Raffaele University)H-Index: 27
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Mechanomedicine is an emerging field focused on characterizing mechanical changes in cells and tissues coupled with a specific disease. Understanding the mechanical cues that drive disease progression, and whether tissue stiffening can precede disease development, is crucial in order to define new mechanical biomarkers to improve and develop diagnostic and prognostic tools. Classically known stromal regulators, such as fibroblasts, and more recently acknowledged factors such as the microbiome an...