COVID-19: fighting the invisible enemy with microRNAs.

Published on Feb 1, 2021in Expert Review of Anti-infective Therapy3.767
· DOI :10.1080/14787210.2020.1812385
Neeraj Chauhan24
Estimated H-index: 24
(University of Texas at Austin),
Neeraj Chauhan10
Estimated H-index: 10
(University of Texas at Austin)
+ 1 AuthorsMurali M. Yallapu34
Estimated H-index: 34
(University of Texas at Austin)
The novel coronavirus (CoV) disease 2019 (COVID-19) is a viral infection that causes severe acute respiratory syndrome (SARS). It is believed that early reports of COVID-19 cases were noticed in De...
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The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to transmission and replication in humans. Although the mutation rate is limited, recently introduced mutations in SARS-CoV-2 have the potential to alter viral fitness. In addition to amino acid changes, mutations could affect RNA secondary structure critical to viral life cycle, or interfere with sequences targeted by host miRNAs. We have analysed subsets of genomes from SARS-CoV-2 isolates from around the globe a...
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