Original paper
Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population
Abstract
Background Pathogenic mutation in BRCA genes causes high cancer risk. Identifying the mutation carriers plays key roles in preventing BRCA mutation-related cancer. Population screening has demonstrated its power for comprehensive identification of the mutation carriers. However, it is only recommended for the Ashkenazi Jewish population with high prevalence of three founder mutations, but not for non-Ashkenazi Jewish populations as the...
Paper Details
Title
Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population
Published Date
Aug 17, 2020
Journal
Volume
58
Issue
9
Pages
587 - 591