Short peptides conjugated to non-peptidic motifs exhibit antibacterial activity
Abstract
Short peptides derived from buforin and lactoferricin B were conjugated with other antimicrobial molecules of different chemical natures. The sequences RLLR, RLLRLLR, RWQWRWQWR, and RRWQWR were conjugated at their N-terminal end with non-peptidic molecules such as 6-aminohexanoic acid, ferrocene, caffeic acid, ferulic acid, and oxolinic acid. Peptide conjugates and unmodified peptides were synthesized by means of solid-phase peptide synthesis...
Paper Details
Title
Short peptides conjugated to non-peptidic motifs exhibit antibacterial activity
Published Date
Jan 1, 2020
Journal
Volume
10
Issue
49
Pages
29580 - 29586
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