Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study
Abstract
To determine the joint role of ideal cardiovascular health (CVH) and genetic risk on risk of dementia.We categorized CVH on the basis of the American Heart Association Ideal CVH Index and genetic risk through a genetic risk score (GRS) of common genetic variants and the APOE ε4 genotype in 1,211 Framingham Heart Study (FHS) offspring cohort participants. We used multivariable Cox proportional hazards regression models to examine the association...
Paper Details
Title
Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study
Published Date
Sep 8, 2020
Journal
Volume
95
Issue
10
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