Original paper
Ochratoxin A induces glomerular injury through activating the ERK/NF-κB signaling pathway
Abstract
Ochratoxin A (OTA) was reported to induce proximal tubules nephrotoxicity in humans and animals. However, the toxicity of OTA on glomeruli has rarely been studied. We investigated OTA-induced glomerular injury and the underlying mechanisms. Mice were intraperitoneally treated with OTA (0, 0.5, 1.5 and 2.5 mg/kg b.w.) on alternate day for 3 weeks. OTA exposure decreased the weight gain ratio, the kidney index and increased the levels of serum...
Paper Details
Title
Ochratoxin A induces glomerular injury through activating the ERK/NF-κB signaling pathway
Published Date
Sep 1, 2020
Journal
Volume
143
Pages
111516 - 111516
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Notes
History