Abstract A80: Targeting ovarian cancer stem cell by Dot1L inhibition
Volume: 26, Issue: 13_Supplement, Pages: A80 - A80
Published: Jul 1, 2020
Abstract
Cancer stem cells (CSCs) are a specific population of cancer cells that are responsible for tumor initiation, chemoresistance, and metastasis. Previously, our lab has demonstrated ovarian cancer cells with high aldehyde dehydrogenase (ALDH) activities have multiple stem cell-like characteristics, including self-renewal, high clonogenicity, and chemoresistance. Here we identify that H3K79 methyltransferase DOT1L (disruptor of telomeric...
Paper Details
Title
Abstract A80: Targeting ovarian cancer stem cell by Dot1L inhibition
Published Date
Jul 1, 2020
Journal
Volume
26
Issue
13_Supplement
Pages
A80 - A80
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