Chronic Granulomatous Disease: a Comprehensive Review
Volume: 61, Issue: 2, Pages: 101 - 113
Published: Jun 10, 2020
Abstract
Chronic granulomatous disease (CGD) is a primary immunodeficiency of phagocyte function due to defective NADPH oxidase (phox). Compared with the common types of CYBB/gp91phox, NCF1/p47phox, and CYBA/p22phox deficiency, NCF4/p40phox deficiency is a mild and atypical form of CGD without invasive bacterial or fungal infections. It can be diagnosed using serum-opsonized E.coli as a stimulus in dihydrorhodamine (DHR) assay. Patients with CYBC1/Eros...
Paper Details
Title
Chronic Granulomatous Disease: a Comprehensive Review
Published Date
Jun 10, 2020
Volume
61
Issue
2
Pages
101 - 113
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