doi.org/10.3389/fcell.2020.00436
Original paper

Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition

..., Rong Jane Chen
22
Frontiers in Cell and Developmental Biology5.50
Volume: 8
Published: Jun 3, 2020
Abstract
Chronic kidney disease (CKD) is recognized as a global public health problem. NLRP3 inflammasome activation has been characterized to mediate diverse aspect mechanisms of CKD through regulation of proinflammatory cytokines, tubulointerstitial injury, glomerular diseases, renal inflammation, and fibrosis pathways. Autophagy is a characterized negative regulation mechanism in the regulation of the NLRP3 inflammasome, which is now recognized as the...
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Paper Details
Title
Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition
DOI
doi.org/10.3389/fcell.2020.00436
Published Date
Jun 3, 2020
Journal
Frontiers in Cell and Developmental Biology
Volume
8
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