Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock

Background Whether hydrocortisone, vitamin C, and thiamine treatment can reduce the mortality of patients with sepsis is controversial. Research Question To evaluate the efficacy and safety of hydrocortisone, vitamin C, and thiamine combination treatment for patients with sepsis or septic shock (HYVCTTSSS). Study Design and Methods This single-blind, randomized controlled trial evaluated treatment with hydrocortisone (50 mg every 6 h for 7...