Internal medicine

Clinical endpoint

Regimen

Nuclear medicine

Cancer

Surgery

Randomized controlled trial

Telangiectasia

Breast cancer

Radiation therapy

Medicine

Journal of Clinical Oncology

Previous studies of hypofractionated adjuvant whole-breast radiotherapy for early breast cancer established a 15- or 16-fraction (fr) regimen as standard. The FAST Trial (CRUKE/04/015) evaluated normal tissue effects (NTE) and disease outcomes after 5-fr regimens. Ten-year results are presented.

Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer